Glycogen synthetase kinase 3 beta is a protein kinase that has been implicated in many types of cancer. Depending on the cell type, the gene for glycogen synthetase kinase 3 beta (GSK 3B) can act either as an
oncogene or as a tumor suppressor.
Which of the following best predicts how GSK 38 mutations can lead to the development of cancer?
A) Cells with inactive GSK 3 Beta fail to trigger apoptosis.
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B) Cells with inactive GSK 3 Beta fail to proceed past the G2/M checkpoint.
C) Cells with overactive GSK 3 Beta are more likely to repair damage.
D) Cells with overactive GSK 3 Beta have longer cell cycles.