HELP! If a person has sickle cell anemia, about 50% of their red blood cells will be sickle shaped. But, this is due to a mutation in the hemoglobin gene which affects the shape of some of the cells. What percentage (%) of the cells in their body will have the abnormal and nonfunctional hemoglobin gene? Why did you choose that number?

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With less oxygen, the abnormal hemoglobin S gene can cause rigid, nonliquid protein strands to form within the red blood cell. These rigid strands can change the shape of the cell, causing the sickled red blood cell that gives the disease its name.

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