Use the chart above to determine which substitution mutation has the potential to cause more damage? Highlight your answer. (2pts) a. Substitution of 3rd N-base to go from CAU to CAC b. Substitution of 3rd N-base to go from UGU to UGC c. Substitution of 3rd N-base to go from UCU to UUU 3. Explain WHY: (3pts)

This question is incomplete

Explanation:

This question is incomplete because of the absence of the chart referred to in the question. However, what appears to be the case is that the three nitrogenous bases represent codons (and the missing chart is the codon chart). The mutation that has the potential to cause more damage will be the one that would change the amino acid formed from the codon change.

A. CAU to CAC: The codons CAU and CAC both form the amino acid histidine and thus is not expected to cause a major damage.

B. UGU to UGC: The codons UGU and UGC both form the amino acid cysteine and thus is not expected to cause a major damage.

C. UCU to UUU: Codon UCU forms the amino acid serine while the codon UUU forms the amino acid phenylalanine. Thus, this eventual change in the amino acid formed has the potential to cause a major damage and thus option C is the correct option.

NOTE that a codon is a sequence of three DNA/RNA nucleotides that corresponds to a single amino acid.

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