The yeast Schizosaccharomyces pombe activates transcription of certain genes in the presence of cAMP. To identify a consensus sequence that responds to cAMP activation, you compare the DNA sequences of 10 different promoters that are activated by cAMP-responsive transcription factors, focusing on the regions of the promoters between nucleotides at positions -100 to -86, where 1 is the first nucleotide copied in the mRNA transcript. From the following data, suggest a consensus sequence responsible for cAMP activation of promoters in this organism. Briefly explain the reason(s) for your choices. 5' 100 -90
A 4 2 1 3 1 0 10 0 1 0 5 2 3
T 0 10 0 1 0 5 2 3 2 1 3 1 0
C 10 1 3 1 0 10 0 1 0 5 2 3 6
G 4 2 1 3 1 0 10 5 2 3 2 1 3