How an improvement in apparatus allows for a greater understanding of cell structure

Me with these questions image attached

What did not occur in the proterozoic eon a)the oxygen levels increase greatly in the atmosphere,b)the emergence of the eukarya , c)muti cella’s eukaryotic organisms began to diversify,d)anaerobic bacteria kept thriving with more oxygen

What is the farthest destination to date for a human spaceflight mission?