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Mr. j, age 42, is a construction worker in las vegas. he recently noticed that a mole on his face seemed to be getting larger and darker. at first he did not worry because he was in the sun a lot and assumed the change may have been caused by sunburn. after a month, not only was the mole larger and darker, but it appeared to be “bumpy.” his doctor diagnosed a malignant melanoma skin cancer following biopsy of the nevus. mr. j reports pain in his right shin that does not go away when he puts his feet up or sleeps. discussion questions 1. relate mr. j’s skin changes to the warning signs for malignant melanoma. (see malignant melanoma.) 2. discuss the normal progression of this malignancy. what is the significance of the bone pain that mr. j is experiencing? (see malignant melanoma.) 3. discuss the treatment available for this patient and the prognosis for recovery. (see malignant melanoma.)

3. draw a topographic map that displays the following features: (4 points each) a. the contour interval is 20 meters. b. the point of lowest elevation is 960 meters. c. the point of highest elevation is 990meters. d. there is at least one sinkhole or depression, at any elevation. e. there is at least one steep slope and one gentle slope.

Ts assignment - snow day assignment genetic variation and natural selection natural selection relies on genetic variation. in any population of beetles, there are alleles for brown or green color. what happens to the genotype and the phenotype of the beetle population when there are distinct advantages and disadvantages due to color? order the steps that take place during natural selection in this beetle population.