Intracellular Ca2 oscillations, initiated by the activation of IP3 receptors and orchestrated via intricate positive and negative feedback loops, can be subject to frequency modulation, an example of which is the increase in oscillation frequency with increasing stimulus strength. Caffeine is known to bind to and sensitize the ryanodine receptors, resulting in their opening in response to lower calcium ion concentrations. Do you think caffeine would tend to increase or decrease the frequency of calcium ion oscillations in stimulated cells

Organisms within a population must compete for resources to survive

The tasmanian devil, a marsupial carnivore, is facing extinction due to devil facial tumor disease (dftd) which causes bulging cancerous lumps and lesions to erupt around the face and neck — often causing enough deformation to make seeing or eating difficult. dftd has evolved into a contagious cancer, a trait that is unique among cancers. devil mating behavior involves biting around the head and neck, allowing cells from one individual — especially cells from the crumbly dftd tumors — to be transferred to the wounds or face of a new individual. this marsupial was once found across australia, but sea levels rose, isolating the tasmanian population, while the australian population went extinct. what would be an outcome of genetic isolation that is likely to have impacted the spread of dftd? a) reduced territory puts diseased individuals in greater contact with non-diseased ones. b) inbreeding results in less variation in facial features so the cancer is generally fatal. c) genetic isolation has made it difficult for scientists to develop a vaccine against dftd. d) the lack of genetic variation in the immune system of tasmanian devils minimizes resistance to the disease.

The rapid decomposition of organic matter produces evidence which supports: the slow accumulation of coal deposits long ages of the earth rapid burial of vast amounts of vegetation biblical account of noah's flood