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Biology, 26.02.2021 23:40 diwashkandel6pe02af
If a mouse is given a dose of radiation sufficient to destroy its immune system,
then injected with purified hematopoietic stem cells, what should happen?
A-
The mouse survives over 3 months and if successful transplantation
of their new HSCs rescues a second lethally irradiated recipient,
they can be considered to have received near pure HSC,
reconstituting their immune system.
B-
The mouse's remaining immune cells will cause a graft versus host
immune reaction, targeting the new HSCs for destruction.
C-
The new HSCs will over proliferate and the mouse will develop
leukemia.
D- the mouse dies as its immune system might attack the HSC.
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