what is the main difference between base pairing during DNA replication and base pairing during transcription

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Explanation:

Replication is a process involving the production of daughter copy by DNA. Transcription, on the other hand, is a process during which the coding strand of DNA is used as a template for the production of mRNA - messenger RNA.

During DNA replication, Adenine is paired with Thymine while Guanine is paired with Cytosine. During transcription, Adenine's pairing is replaced with Uracil while Guanine/Cytosine pairing remains the same.

hence, the main difference between the base-pairing during both processes is the replacement of Thymine with Uracil during transcription.

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explanation: