The recent manuscript "Biomechanics: Cell Research and Applications for the Next Decade" Ann Biomed Eng. 2009 May;37(5):847-59, by Discher, Dong, Fredberg, Guilak, Ingber, Janmey, Kamm, Schmid-Schönbein and Weinbaum discusses the challenges for cell mechanics now and in the future. 4.1 Read the manuscript carefully and summarize it with approximately 150 words (do not copy abstract). 4.2 The authors have identified ten major accomplishments in cell mechanics. List all the ten accomplishments by title. 4.3 Select your favorite past accomplishment and describe it in less than 100 words. 4.4 The authors have identified seven major challenges for the future. List all the seven future challenges by title. 4.5 Select your favorite future challenge and describe it in less than 100 words.