What is the best topic sentence for an article about whether or not certain genes play a favorable role in human evolution?

"jumping genes," or transposable elements, are dna sequences that have the ability to replicate and move from one chromosome to another.
nobel laureate barbara mcclintock first reported this phenomenon in 1951, but few other scientists believed her findings at the time.
jumping genes have the unsavory reputation of causing genetic mutation or cancerous cell growth.
challenging the notion that jumping genes are "junk" genes, recent b