What causes the release of the digestive enzyme pepsin

The hormone gastrin and the vagus nerve trigger the release of both pepsinogen and HCl from the stomach lining when food is ingested. Hydrochloric acid creates an acidic environment, which allows pepsinogen to unfold and cleave itself in an autocatalytic fashion, thereby generating pepsin (the active form).

you must remain stopped until the stop signal is retracted and the red lights are turned off. approaching traffic in the opposite roadway of a divided highway shall not be required to stop, even if the school bus has the stop-arm extended and the alternately flashing warning signal lamps on.

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