How would a dislodged piece of plaque in the cardiovascular system most likely affect an otherwise healthy person? the right pulmonary artery could become blocked, restricting blood flow to the right lung. a narrow region of the superior vena cava could become blocked, restricting blood flow to the heart. a smaller artery in a leg could become blocked, restricting blood flow to capillaries in the leg. a narrow vein in the brain could become blocked, restricting blood flow to capillaries in the brain.