What is the mechanism by which binding of testosterone to the testosterone receptor leads to upregulated gene transcription

This binding causes a conformational change in the receptor which enters into the nucleus and binds DNA to activate transcription

Explanation:

Testosterone is a steroid hormone responsible for inducing protein synthesis and growth of tissues with androgen receptors. Testosterone receptors, also known as androgen receptors, are a class of nuclear receptors activated by binding androgenic hormones (e.g. testosterone) in the cytoplasm, whose binding induces a conformational change of the receptors that are subsequently translocated to the nucleus. Within the cell nucleus, these activated receptors form homodimers that bind DNA in order to promote the transcription of target genes capable of regulating cell growth, cell cycle progression and survival.

ans.

dna fingerprinting is defined as a process that determines the dna characteristics of an individual. these dna characteristics are unique among individuals as their fingerprints, so it is known as dna fingerprinting.

steps of dna fingerprinting includes extraction of dna from sample, amplification of dna, restriction digestion of amplified dna, and then analysis of dna by gel electrophoresis, respectively.

thus, the next step performed by the scientist is 'to cut the amplified dna (obtained by polymerase chain reaction) by restriction enzymes that cleave the dna into fragments and their analysis.'