When donor MHC:donor self-peptide complexes activate recipient T cells, . Group of answer choices suppression occurs and transplanted organs are tolerated an indirect pathway of allorecognition occurs hyperacute rejection of transplanted organs occurs acute rejection of transplanted organs occurs complement pathways are activated

acute rejection of transplanted organs occurs

Explanation:

In vertebrates, the major histocompatibility complex (MHC) locus contains genes responsible for encoding cell surface proteins (MHC molecules) that play essential roles in the adaptive immune system. In the last years, it has been shown that the cell environment is controlled by the immune system through the major histocompatibility complex (MHC). An antigen is any substance capable of triggering an immune response. MHC captures endogenous peptides and antigens in order to be examined by the immune system. Thus, antigen presentation by MHC can trigger the process of immunological rejection during transplantation. Recognition of donor antigens by T lymphocytes triggers a consequent inflammatory immune response that leads to the rejection of the transplant. These T cells are activated by the interaction of T cell receptors with allogeneic MHC molecules on donor cells.

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