What are the components of the extracellular matrix of bone? Blood? Describe how these different matrices contribute to the different functions of bone and blood?

The Bone Extracellular Matrix in Bone Formation and Regeneration

Explanation:

Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio-environment with precisely regulated mechanical and biochemical properties. In bone, ECMs are involved in regulating cell adhesion, proliferation, and responses to growth factors, differentiation, and ultimately, the functional characteristics of the mature bone. Bone ECM can induce the production of new bone by osteoblast-lineage cells, such as MSCs, osteoblasts, and osteocytes and the absorption of bone by osteoclasts. With the rapid development of bone regenerative medicine, the osteoinductive, osteoconductive, and osteogenic potential of ECM-based scaffolds has attracted increasing attention.

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anti-human il1 beta stable cell line (gevokizumab) can be provided from creative biolabs.

explanation: