Which of the following are mechanisms utilized by cells to resist the effects of an antimicrobial agent? SELECT ALL THAT APPLY

Group of answer choices

They may abandon metabolic pathways, and instead begin acquiring the metabolite from their environment.

They may alter the target of the drug to prevent the antimicrobial from binding to the target.

They may utilize membrane-localized efflux pumps that act to remove the antimicrobial from the cell.

The may change the structure or charge of pore proteins thereby preventing entry of the antimicrobial agent

They may secrete enzymes that destroy the chemical structure of the antibiotic.