Which of the following statements is false? Question 1 options: Bcl2 blocks aggregation of BH123 on the outer mitochondrial membrane thus inhibiting apoptosis. BH123 proteins, like Bax and Bak, are death-promoting members of the Bcl2 family that induce the release of cytochrome c from mitochondria into the cytosol. Bcl2 proteins are part of the extrinsic apoptosis pathway. Some Bcl2 family members promote apoptosis, whereas others inhibit apoptosis.

The correct answer is - Bcl2 proteins are part of the extrinsic apoptosis pathway.

Explanation:

The Bcl-2 family group of proteins that are known to either promote or inhibit the process of apoptosis by regulating the mitochondrial membrane potential. Bax and Bak are Bcl-2 proteins, act as pro-apoptotic proteins which oligomerize to result in forming pores in the membrane of the mitochondria.

These pores lead to the release of cytochrome c to the cytoplasm. Bcl-2 protein is an anti-apoptotic protein that inhibits the oligomerization of Bak and Bax.

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