Inherited defects in components of purine catabolism and salvage are associated with various conditions and syndromes. The enzyme hypoxanthine-guanine (HGPRT) is a key enzyme in the purine salvage pathway. It is responsible for reforming IMP and GMP from hypoxanthine and guanine, respectively. In this manner purine bases are salvaged back into the purine nucleotide pool. Genetic defects that lead to the loss of HGPRT activity are the primary cause for which of the following conditions? a. Gout
b. Lesch-Nyhan syndrome
c. Orotic aciduria
d. Severe combined immunodeficiency syndrome
e. Tay-Sachs disease

Which best describes meiosis? a. it produces cells that are identical to the original cell b. it is responsible for the replacement of damaged skin cells c. it is responsible for growth of the organism d. it produces male and female sex cells

Coat color in cats is determined by genes at several different loci. at one locus on the x chromosome, one allele (x ) encodes black fur and another allele (xo) encodes orange fur. females can be black (x x ), orange (xoxo), or a mixture of orange and black called tortoiseshell (x xo). males are either black (x y) or orange (xoy). bill has a female tortoiseshell cat named patches. one night, patches escapes from bill\'s house, spends the night out, and mates with a stray male. patches later gives birth to the following kittens: one orange male, one black male, two tortoiseshell females, and one orange female. what are the genotypes of patches, the stray male, and the kittens?

For this question look at the hydropic diagram water that is heated by the sun evaporates. select the number that represents it.