Because the mutation is on the surface, loss of Because the mutation is on the surface, loss of blank contacts in the protein core is blank and the amino acid is likely to be interacting with solvent to blank extents in both folded and unfolded states; thus, effects on blank are predicted to be minimal. contacts in the protein core is Because the mutation is on the surface, loss of blank contacts in the protein core is blank and the amino acid is likely to be interacting with solvent to blank extents in both folded and unfolded states; thus, effects on blank are predicted to be minimal. and the amino acid is likely to be interacting with solvent to Because the mutation is on the surface, loss of blank contacts in the protein core is blank and the amino acid is likely to be interacting with solvent to blank extents in both folded and unfolded states; thus, effects on blank are predicted to be minimal. extents in both folded and unfolded states; thus, effects on Because the mutation is on the surface, loss of blank contacts in the protein core is blank and the amino acid is likely to be interacting with solvent to blank extents in both folded and unfolded states; thus, effects on blank are predicted to be minimal. are predicted to be minimal.