Bacteria such as e. coli and salmonella produce invasins that bind host cells, thus causing the cells to:

kill cells and tissues outright

Explanation:

Sometimes bacteria multiply so rapidly they crowd out host tissues and disrupt normal function. Sometimes they kill cells and tissues outright. Sometimes they make toxins that can paralyze, destroy cells' metabolic machinery, or precipitate a massive immune reaction that is itself toxic

Acrroding to http://needtoknow.nas.edu/id/infection/how-pathogens-make-us-sick/