During cell division a piece of a chromosome breaks off and reattaches to the same chromosome, but the piece is now in reverse order. How would this abnormality affect the chromosome

According to theories of how life began, how did early organic molecules begin to separate from the outside world? a: specialized enzymes were required b: chains of amino acids created a barrier c: formation of microspheres or vesicles d: rna catalyzed the formation of membranes