Explain how natiral selection is responsible for distribution of allel abnormal form of haemoglobin

igneous rocks are formed by solidification of cooled magma (molten rock), with or without crystallization, either below the surface as intrusive (plutonic) rocks or on the surface as extrusive (volcanic) rocks.  

the composition depends on the source magma. there are almost a thousand types of composition found till now.  

hope this

loss of sensation to pressure and touch

the dorsal column–medial lemniscus pathway (dcml) (also known as the posterior column-medial lemniscus pathway (pcml)) is a sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (position) from the skin and joints.