You have joined a lab studying dna replication in e. Coli. The graduate student you are working with has identified a mutation in primase that makes primase very inefficient. Your project is to characterize the cells with this mutation. Predict the defects you would most likely see in the mutant e. Coli cells.

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osteogenesis imperfecta (oi) refers to a congenital ailment of bones. in the condition, the bones become brittle or fragile. this ailment is a general result of the defect or mutations in the genes (colia1 or colia2). this mutation results in imperfect collagen formation either in quantity or quality wise.  

there are eight kinds of oi defects, and each kind varies with certain distinctions in symptoms. the usual symptoms include frequent bone fractures, loss of hearing in infants, protruding eyes, discoloration of the white in the eyes, respiratory issues, loosening of the joints, short stature, and other symptoms.