Which of the following statements best describes the major difference between metaphase i of meiosis and metaphase of mitosis? (2 points) in metaphase i, tetrad sets of homologous chromosomes stay together as they line up along the center of the cell. in metaphase, homologous chromosomes are separated as each sister chromatid set is pulled to one end of the cell. in metaphase, sister chromatids are separated and pulled apart to form a total of four new haploid cells. in metaphase i, sets of sister chromatids line up at the center of the cell and the spindle fibers pull them apart.