"thymocyte progenitors enter the subcapsular region of the thymus as double-negative cd3- t cells where the double negative refers to lack of cluster and "

The Thymocyte progenitors enter the subcapsular region of the thymus as double-negative cd3- t cells where the double negative refers to lack of cluster determinants CD4 and CD8. Double-negative cd3- t cells exist as small population that is 1%-5% of lymphocytes in the lymphoid organs and peripheral blood of humans and normal rodents.