Which of these parts of the membrane large molecules pass through it?

Integral membrane proteins or globular protein

Explanation:

Integral membrane proteins play an important role in passing ions and large polar molecules through the membrane by active or passive transport.

The proteins at the gated channels enable transportation of water and other hydrophilic molecules.

In general, a hydrophilic molecules bind to a "carrier" protein to facilitate the passive transportation

However, in active transport, hydrophilic molecules bind to a carrier protein along with utilization of energy against their concentration gradient

desert perennials often survive by remaining dormant during dry periods of the year, then springing to life when water becomes available. most annual desert plants germinate only after heavy seasonal rain, then complete their reproductive cycle very quickly.