The reduced self-control of impulsive murderers is most closely related to reduced brain activity in their lobes.

There is a brain reduce activity in the frontal lobe. The frontal lobe is located at the front of the brain, is the biggest of the four major lobes of the cerebral cortex in the mammalian brain. The frontal lobe can be seen at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is separated from the parietal lobe by a groove between tissues called the central sulcus, and from the temporal lobe by a deeper groove called the lateral sulcus (Sylvian fissure).

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the solute can move "downhill," from regions of higher to lower concentration, relying on the specificity of the protein carrier to pass through the membrane. this process is called passive transport or facilitated diffusion, and does not require energy.