The hypothesis was that all three segments of the regulatory region are required for highest expression of the hoxd13 gene. is this hypothesis supported by the results? the hypothesis was that all three segments of the regulatory region are required for highest expression of the hoxd13 gene. is this hypothesis supported by the results? no; they did not delete the promoter, so the gene could still be expressed even without the segments. no; even when segments were deleted, the hoxd13 gene was still being expressed. yes; when any of the segments were deleted, the expression level dropped to less than 100% of the control. yes; when all three segments were present, the expression level was at 100%.