What happens when an air bubble passes through the buret in a titration?

Assume that the reaction is

this protocol provides a detailed procedure for co-immunoprecipitation (co-ip) to identify protein–protein interactions.

affects the water bodies: excessive use of fertilizers causes eutrophication. the fertilizers which are used on plants affect the quality of land on which it is used, further causing erosion of soil. the fertilizers used on plants contain harmful chemical fumes which affect the environment.