The recessive allele that causes sickle cell anemia is harmful to homozygous individuals. what maintains the presence of this allele in a population's gene pool?

The one responsible for maintain the presence of this allele in the population’s gene pool is the heterozygote advantage. It is because the advantage of having this for a sickle cell disease is that if a person has a strong heterozygote advantage and that he or she has a copy of the allele that cause the sickle cell disease, the person will likely be resistant to the disease because of the heterozygote advantage in which the heterozygote genotype has a higher relative fitness making it resistant to the disease.

humans, along with other animals and plants, have linear chromosomes that are arranged in pairs within the nucleus of the cell. the only human cells that do not contain pairs of chromosomes are reproductive cells, or gametes, which carry just one copy of each chromosome.