Na lab you are conducting tests with various chemicals and neurotransmitter receptors. you notice that exposed frog muscle cells depolarize when you add the chemical nicotine to the acetylcholine (ach) receptors. what does this tell us about the relationship between neurotransmitters and their receptors? in a lab you are conducting tests with various chemicals and neurotransmitter receptors. you notice that exposed frog muscle cells depolarize when you add the chemical nicotine to the acetylcholine (ach) receptors. what does this tell us about the relationship between neurotransmitters and their receptors? the effect of a neurotransmitter is based on the properties of the neurotransmitter more than the receptor. neurotransmitter receptors only bind specifically with their neurotransmitter. the effect of a neurotransmitter is based on the properties of the receptor more than the neurotransmitter. the response generated by a receptor is very broad in nature.