Which of the following hereditary conditions is characterized by abnormally shaped blood cells? acne. heart disease. sickle cell anemia. type 1 diabetes.

sickle cell

Explanation:

Sickle cell anemia

Explanation:

Hemoglobin serves to carry oxygen and is present in red blood cells. Sickle cell anemia is caused by a point mutation in one of the hemoglobin gene that codes for its beta chain. The mutated allele of the beta globin chain encodes the abnormal hemoglobin molecules which stick to one another resulting in sickle shaped red blood cells.

we solve the problem using the hardy-wineberg equation.

let us start with the homozygous recessive proportion of individuals with sickle cell anaemia,

we have the proportion as q² = 0.25.

∴ q = 0.5 (frequency of hbs in population)

further,

solving for the frequency of normal cell by using the fact that,

p + q = 1

∴ p = 1 - 0.5 = 1 - 0.5 = 0.5

now we can calculate 2pq in p² + 2pq + q², which is the frequency for heterozygous carriers of sickle cell anaemia,

∴ 2pq = 2 x 0.5 x 0.5 = 0.5

and the homozygous normal cell individuals proportion is given by the expression,

∴ p² = 0.5² = 0.25

hence, the carriers for sickle cell anaemia are in proportion, 0.5, or 50%.