Instrumental methods need only a microscopic sample to return an accurate result. why is this so?

Instrumental methods of analysis rely on machines.The visualization of single molecules, single biological cells, biological tissues and nanomaterials is very important and attractive approach in analytical science.
There are several different types of instrumental analysis. Some are suitable for detecting and identifying elements, while others are better suited to compounds. In general, instrumental methods of analysis are:
-Fast
-Accurate (they reliably identify elements and compounds)
-Sensitive (they can detect very small amounts of a substance in a small amount of sample)