Chemistry, 09.12.2019 22:31 rwallacejr803
In nucleophilic acyl substitution, in nucleophilic acyl substitution, loss of the leaving group is followed by rearrangement of the carbocation. protonation of the carbonyl is followed immediately by loss of the leaving group. ester hydrolysis is followed by deprotonation. an sn2 reaction occurs. addition to the carbonyl by a nucleophile is followed by loss of the leaving group.
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