Hydrophobic molecules (like oil) tend to self-associate in water rather than dissolve. what is the major energetic contribution to this property.

The MAJOR energetic contribution to this property is the self association that maximizes the entropy of the water molecules.

Explanation:

Hydrophobic molecules (like oil) tend to self-associate in water rather than dissolve in it. The MAJOR energetic contribution to this property is the self association of this oil which increases the degree of disorderliness of the water molecules.

The self association maximizes the entropy of the water molecules

Explanation:

Nonpolar molecules, like Oil, do not dissolve easily in water. They are described as hydrophobic, or water fearing. When put into polar environments, such as water, nonpolar molecules stick together and form a tight membrane, preventing water from surrounding the molecule.

Moreso, the hydrophobic effect was found to be entropy-driven at room temperature because of the reduced mobility of water molecules in the solvation shell of the non-polar solute.