During pre-clinical research, a starting lead compound usually requires optimization of one or more of its properties. What is not a property of a lead compound that researchers attempt to optimize?
a) Decreasing the drug's adverse health effects
b) In some diseases, like certain cancers, broaden inhibition of multiple targets"
c) Increase the leads potency at lower concentrations
d) Enhance the drug's distribution to non-target cells in the patient
e) Improving binding specificity of the drug to a target protein

)in the deacon process for the manufacture of chlorine, hcl and o2 react to form cl2 and h2o. sufficient air (21 mole% o2, 79% n2) is fed to provide 35% excess oxygen, and the fractional conversion of hcl is 85%. calculate the mole fractions of the product stream components.

Benzonitrile (c6h5cn) is reduced to two different products depending on the reducing agent used. treatment with lithium aluminum hydride followed by water forms k, which has a molecular ion in its mass spectrum at 107 and the following ir absorptions: 3373, 3290, 3062, 2920, and 1600 cm-1. treatment with a milder reducing agent forms l, which has a molecular ion in its mass spectrum at 106 and the following ir absorptions: 3086, 2850, 2820, 2736, 1703, and 1600 cm-1. l shows fragments in its mass spectrum at m/z = 105 and 77. propose structures for k and l and choose an explanation for how this could be concluded.

Astable atom that has a large nucleus most likely contains 1. more neutrons than protons. 2.more protons than neutrons. 3.equal numbers of protons and neutrons. 4.changing numbers of protons and neutrons.