subject
Chemistry, 21.04.2020 17:24 Siris420

The Stork enamine reaction and the intramolecular aldol reaction can be carried out in sequence to allow the synthesis of cyclohexenones. For example, reaction of the pyrrolidine enamine of cyclohexanone with 3-buten-2-one, followed by enamine hydrolysis and base treatment, yields the product indicated. The mechanism involves the following steps: Michael addition of the enamine to the unsaturated ketone yields carbanion 1; Proton transfer leads to enamine 2; Hydrolysis of the enamine leads to cyclohexanone 3; Deprotonation leads to carbanion 4; Intramolecular aldol addition leads to tetrahedral intermediate 5; Protonation leads to aldol addition product 6; Dehydration leads to the final product. Write out the reaction mechanism on a separate sheet of paper, and then draw the structure of tetrahedral intermediate 5.

ansver
Answers: 1

Another question on Chemistry

question
Chemistry, 21.06.2019 14:00
The study of witch tree monkeys feed in is part of the science life
Answers: 1
question
Chemistry, 21.06.2019 17:00
What is the nature of the ca-cl bond in a molecule of calcium chloride (cacl2) if the electronegativity value of calcium is 1.0 and that of chlorine is 3.16?
Answers: 1
question
Chemistry, 21.06.2019 19:10
Nuclear fusion is the source of energy for stars. besides hydrogen, which other element is most likely also common in stars?
Answers: 1
question
Chemistry, 21.06.2019 21:30
Why does a red shoe appear red in daylight
Answers: 2
You know the right answer?
The Stork enamine reaction and the intramolecular aldol reaction can be carried out in sequence to a...
Questions
question
Mathematics, 18.12.2020 21:10
question
Mathematics, 18.12.2020 21:10
Questions on the website: 13722361