Therapeutic drugs generally need to have some hydrophobic and hydrophilic components to be able to effectively reach their target organs and tissues given there are aqueous and nonaqueous parts of the body. The degree to which a compound is hydrophobic and hydrophilic can be determined by measuring its relative solubility in water and octanol, C8H17OH, and water. To do this, a sample of the compound is added to a mixture of water and octanol and mixed well. Water and octanol are immiscible so after the mixture settles, the concentration of the compound in water and the concentration of the compound in octanol is measured. The ratio of the concentrations is called the partition ratio:

Fill in the coefficients that will balance the following reaction: a0cr2(so4)3 + a1agno3

Show transcript transcripts online experiment: atomic structure [the history of atomic theory] this animation will you test rutherford’s hypothesis that it took a great number of shots to actually hit the nucleus because the size of the atom was so much larger than the nucleus.[clipboard and pencil with a diagram of rutherford’s gold foil experiment] we are going to use a cardboard box to represent the atom, a wooden block to represent the nucleus, and marbles to represent the alpha particles. [animated cardboard box, wooden block, and marbles] the box’s measurements are: length = 50 cm, width = 25 cm, and height = 25 cm. the measurements of the block are: length = 10 cm, width = 10 cm, and height is 5 cm. jose and priscilla will conduct the experiment. [animated boy and girl] priscilla put the block in the box on the floor. jose will close his eyes and drop marbles into the box trying to hit the block. priscilla will count the number of times the marbles hit the block and move the block in the box after each hit. [animated block moving inside the box. marble dropping into the box.] here is priscilla’s data of how many times the marble hit the block. out of 100 marble drops or shots, the marble hit the block 32 times. [data table: first column: marble, with rows 1 to 100; column 2: hit, with rows indicating yes or no. last row: total hits] now you can follow the directions in the experiment to present your findings. present your findings when you are finished with the experiment, complete the following data analysis and record your answers in the essay box below. determine the volume of the box and the block. determine the ratio of the block to the box: multiply this number by 100 to turn it into a percent. complete this statement: the volume of the block is percent of the volume of the box. determine the ratio of the number of hits to the number of shots: multiply this number by 100 to turn it into a percent. complete this statement: the block was hit percent of the time. compare the results of step 2 to the results of step 3. are the percentages similar? write a conclusion discussing the following items: based on your findings, do you think rutherford's hypothesis was reasonable? restate rutherford's hypothesis and describe how you tested it. state whether your results support the hypothesis. if they do not, can you suggest some error in experimental procedure (other than general human error) that might explain it? finally, explain how this experiment confirms the nuclear model of the atom and the idea that most of the atom is empty space.

Adirect relationship can be represented by: a curve a pie chart