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The  grandmother cell  is a hypothetical  neuronthat represents a complex but specific concept or object.[1]  it activates when a person "sees, hears, or otherwise sensibly discriminates"[2]  a specific entity, such as his or her grandmother. the term was in use at least as early as 1966 amongst staff and students in the department of experimental psychology, university of cambridge, england. a similar concept, that of the  gnostic neuron, was proposed two years later

Mass is the amount of matter in an object.  weight is the measurement of the pull of gravity on an object.  say for example, you travel to the moon which has a different gravitational field compared to the gravitational field of earth. (gravitational fields: earth = 1, moon = 0.165)  now when you are on the moon, the pull of gravity on you is different than on the earth. and as weight is the measurement of the pull of gravity on an object, that means yes, your weight can and will change on the moon.  however, on the moon, on earth or even on jupiter, the amount of mass inside of you remains the same. meaning your physical mass remains constant.  in conclusion it is possible for your weight to change as your mass remains constant.