N-Tosylamido-L-phenylethyl, also called tosyl phenylalanyl chloromethyl ketone (TPCK), irreversibly inhibits chymotrypsin, and is used to label the active site histidine residue. The COCH2Cl group is the reactive group that binds to the His residue. T P C K is an amino acid analog of phenylalanine where the carboxyl group is replaced by COCH2Cl and the amine is attached to SO2 bonded to benzene with a methyl group in the para position. Why does chymotrypsin bind TPCK?

a. TPCK is a polar molecule and easily forms several non-covalent interactions with the active site Of chymotrypsin, reversibly outcompeting the usual substrate.
b. The chlorine of TPCK is a strong nucleophile, and attacks the His 157 residue.
c. The serine residue at position 195 in chymotrypsin is a strong nucleophile.
d. The phenyl group Of TPCK is structurally similar to regular chymotrypsin substrates.

y = -2x 2 + 3x - 1 and x + y = -1.

Explanation:

y = -2x 2 + 3x - 1 and x + y = -1.

answer: option (b) is the correct answer.

explanation:

a covalent bond is formed by sharing of electrons. whereas polarity arises due to difference in electronegativity of two atoms.

therefore, more is the electronegativity of an atom which combines with the titanium, more readily it will induce a partial positive and negative charge.

thus, out of the given options fluorine is most electronegative and has an incomplete octet. therefore, it will readily combine with titanium to share the electrons and complete its octet.  

definition

                    entropy is a measure of the randomness or the extent of disorder of a chemical process.

                      enthalpy is a measure of the heat change of a reaction occurring at a constant pressure.

measurement units:

                        entropy is measured in joule per kelvin (jk⁻¹)   whereas enthalpy is measured in joule per mole (jmol⁻¹)

requirements:

                            entropy has no requirements or limits, and its change is measured by the division between the heat change of the chemical process and the temperature.

                              in contrast, enthalpy can only be related to the heat change of the reaction under standard conditions.