) Considering the mechanism for this decarboxylation and the ones we saw in class (ex. malonic and acetoacetic ester synthesis), why do you think TPP is necessary to facilitate the decarboxylation of pyruvate

2b2t

explanation:

2b2t

a. energy is absorbed in the reaction.

if in a given reaction the energy of products is greater than the energy of reactants it means that reaction is endothermic and during the reaction, the energy is absorbed by reactants. in an endothermic reaction, the products have more stored chemical energy than the reactants. and in this reaction the reactants are more stable than products before the compounds with less energy are always more stable.