What is the type of mutation represented by the amino acid sequence below? Correct sequence: Leucine – Alanine – Glycine – Leucine
Mutated sequence: Leucine – Alanine – Valine – Leucine

Substitution mutation

Explanation:

A substitution mutation is a type of mutation in which one or more nucleotide base is replaced by another in a sequence. This will result in the replacement of one or more amino acid in the amino acid sequence.

This is the case in this question where the original amino acid sequence was given as: Leucine – Alanine – Glycine – Leucine. After mutation, the following mutated sequence was produced: Leucine – Alanine – Valine – Leucine.

As illustrated above, one would notice that there is replacement of GLYCINE amino acid by VALINE in the mutated sequence, hence, it is an example of SUBSTITUTION MUTATION.