1 Give the mechanism for the synthesis of tyrbostin from benzaldehyde. Show how
the carbanion is generated from malononitrile (NCCH2CN) and stabilised (5 marks).
Show the reaction of the carbanion with the benzaldehyde (5 marks). Show how the
resulting alkoxide (O-) is protonated (5 marks). Show how the alkene bond is formed
(5 marks)
CN
ON
&
NCCH2CN
Piperidine
Aldehyde
Tyrphostin
ted Kingdom)
Focus
Answers: 1
Chemistry, 22.06.2019 14:30
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Answers: 3
Chemistry, 22.06.2019 19:30
What is the mass of oxygen gas is consumed in a reaction that produces 4.60mol so2
Answers: 3
Chemistry, 22.06.2019 20:40
Select the correct value for the indicated bond angle in each of the compounds. o−o−oo−o−o angle of o3 90° 109.5° < 109.5° 120° < 120° 180° f−b−ff−b−f angle of bf3 180° < 109.5° < 120° 120° 109.5° 90° f−o−ff−o−f angle of of2 < 120° 120° 90° 109.5° 180° < 109.5° cl−be−clcl−be−cl angle of becl2 90° 109.5° 180° 120° < 109.5° < 120° f−p−ff−p−f angle of pf3 90° 109.5° < 109.5° 180° 120° < 120° h−c−hh−c−h angle of ch4 90° < 109.5° 180° 120° < 120° 109.5°
Answers: 1
1 Give the mechanism for the synthesis of tyrbostin from benzaldehyde. Show how
the carbanion is ge...
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