How molecular structure affects solubility?

The molecular structure affects solubility mainly biased on its polarity or bonded ions.

Explanation:

Polar molecules will better interact with the water molecules and will dissolve easier. Nonpolar molecules can dissolve if they are small enough, however they don't interact well with the polar molecules. Bonded ions, such as NaCl split into a cation Na and an anion Cl which the positive charge on the Na will be attracted to the oxygen, and the negatively charged Cl will be attracted to the positive Hydrogen.

**Remember this rule, like dissolves like, meaning nonpolar dissolves nonpolar and polar dissolves polar.

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