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Engineering, 18.06.2020 06:57 reese4232

After a brief search of the Toxicology Data Network and cross-referencing with the compounds you identified so far in lavender, you notice cineole, a known phytochemical used in pesticides. This chemical interests you as you read a paper published by Dr. Mitchell Erickson MD about this harmful pesticide being detected in breast milk from residents in Jersey City, NJ. You know that in low doses this chemical increases the absorption of chlorohexidine (a chlorine containing chemical used to disinfect skin before surgery) and other chlorinated chemicals by the activity of glucuronyltransferase, a key enzyme in drug metabolism and detoxification. You noticed this enzyme opens cineole's epoxide ring in an SN1 characteristic. This is advantageous to you since in it's epoxide form cineole cannot be easily seperated from water without decomposing it and an alcohol can be dehydrated in the presence of a strong acid and mild heating. Unfortunately, this newly converted cycloalkene exists at equilibrium with it's alcohol derivative. Propose a method to get the purified cyclolkene (there are several).

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