Cite the evidence that suggests sugar substitutes may not you lose weight. “for one thing, ayoob says it’s not healthy to rely on super-sweet food all the time.” “this means they give a sweet taste without the calories.” “you might discover that a no-sugar-added dessert contains extra fat to give the food the right texture.” “the calorie control council. . claims rats in labs don’t tell us how humans will respond to sweeteners.”