The Dunkers are a religious group that moved from Germany to Pennsylvania in the mid - 1700s. They do not marry with members outside their own Immediate community. Today, the hunkers are genetically unique and differ in gene frequencies, at many loci, from all other populations including those in their original homeland Which of the following likely explains the genetic uniqueness of this population?

population bottleneck and Hardy Weinberg equilibrium
heterozygote advantage and stabilizing selection
mutation and natural selection
founder effect and genetic drift
heterozygote advantage and sexual selection