If you spike someones drink what happens and what is it?

Depends on what you are spiking it with?  If you are spiking a soda with alcohol the person gets drunk.  But if you are talking about drugs it depends on the drug.

If you are asking about spiking a drink with a drug that makes the person unable to remember and become semi conscious I think you are talking about rohypnol.  It is also known as the date rape drug, roofies, etc.  This is a very dangerous drug and was originally used to sedate patients before a medical procedure.  Is that what you wanted?

The best way is to swollow and hold in your breath

Well if you pick a machine to work on and that's gonna be your exercise if you don't stick to that machine your muscle strength your muscle mass rather will change because you haven't been doing it you change something in your exercise routine which changes your body's form of dealing with things for example you might become weaker or stronger depending on what kind of exercises you do in whether or not the machine you picked actually your muscles grow.