Cortisol you maintain energy and health during stressful times. but over a long period of time, cortisol can
decrease your chances for sickness
increase your chance for liver disease
increase your mental clarity
wear away your immune system

Depression is lifelong, though you can get medication to with it. the difference between sadness and depression is that sadness lasts a little bit, depression last a long time and it goes on and off. people usually get depression through experiences they have been through, or genetics.

Cis the